FIGURE

Fig 4

ID

ZDB-FIG-250906-81

Publication

He et al., 2025 - Deficiency of Kif15 impairing synaptic development leads to mood disorder in mice

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Fig 4

Kif15 deficient mice exhibit both depressive and manic behaviors in adulthood.

A-D: Kif15^-/- mice exhibited longer immobility times in Tail suspension test and the forced swimming test at 9, 12, 16, and 20 week-old, n = 7 or 8 in WT group, n = 8 or 9 in Kif15^-/- group; E: Representative tracking path for Kif15^-/- and Kif15 WT mice during 10 minutes open field test in 9, 12, 16 and 20 week-old. F: Kif15^-/- mice traveled further in the 10 minutes open field test at 16 and 20 week-old; n = 8 in WT group, n = 9 in Kif15^-/- group, G: Schematic of the mechanism by which Kif15^-/- mice exhibit depression and mania. The image was created with Microsoft Power Point, and some icons are free downloaded from OPENCLIPART (https://openclipart.org/). All the data are presented as mean±SD, *P < 0.05, **P < 0.01,two-tailed student’s t test between two groups.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

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