FIGURE

Fig. 3

ID

ZDB-FIG-250725-22

Publication

Deng et al., 2025 - Gremlin1 repression-mediated mitochondrial network hyperfunction contributes to TCE-induced zebrafish cardiac defects

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Fig. 3

TCE exposure induced cardiac defects in Tg(grem1a:EGFP) zebrafish embryos. A The schematic diagram of Tg(grem1a:EGFP) line generation. B Representative fluorescent images of Tg(grem1a:EGFP) zebrafish embryos at 2 hpf and 12 hpf with corresponding statistical graph below (n = 30). C Representative fluorescent images of lateral view and ventral view of the heart at 72 hpf (n = 30). Dotted black lines depict heart, arrows indicate atrioventricular valve (blue) or trabeculae of myocardium (red). Heart function parameters including D ejection fraction, E stroke volume, F factional area change and G fractional shortening of zebrafish embryos at 72 hpf. Ctrl, control. TCE, trichloroethylene, 760 nM. *, P < 0.05; **, P < 0.01; ***, P < 0.001 vs control

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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