FIGURE

Fig. 5

ID

ZDB-FIG-250710-27

Publication

Haripriya et al., 2025 - Evaluation of synergistic effect of Zerumbone with Cisplatin on anti-angiogenic potential in zebrafish model

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

Anti-angiogenic effects of CIS, ZER, and their Combination dose on VEGF- A, VEGFR-2, NRP- 1A, NRP- 2B gene expression in zebrafish larvae. A indicates the down-regulated VEGF-A mRNA expression, irrespective of the treatment groups. Maximal down-regulation was observed in zebra fish undergone ZER treatment. B states the subnormal down-regulation of VEGFR-2 mRNA expression in ZER and combination treatment groups than CIS alone treated larvae. C Note the moderate significant (p < 0.001), reduction in NRP-1A mRNA expression in ZER, and combination treatment, whereas in CIS treatment mild significant decrease in NRP-1A gene expression was observed. D illustrates the significant down-regulation of NRP-2B gene expression in CIS, and combination treated group. Comparatively, the effect on NRP-2B gene expression was highly up-regulated in the ZER treated group

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Med Oncol