FIGURE

Figure 9

ID

ZDB-FIG-250417-148

Publication

Lin et al., 2025 - Identifying Baicalein as a Key Bioactive Compound in XueBiJing Targeting KEAP1: Implications for Antioxidant Effects

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Figure 9

QPCR and Western blot results. (A) Gene and protein expression in MCF-7 cell lines treated by baicalein. * p < 0.05 vs. CTRL; ** p < 0.01 vs. CTRL; *** p < 0.001 vs. CTRL; **** p < 0.0001 vs. CTRL. MCF-7 cell lines were transfected with ncr, siKEAP1, or siNRF2. Cells were then treated with baicalein (8.772 mg/mL) for 24 h. (B) siKEAP1 and siNRF2 knockdown silencing efficiency. (C) Control groups with no drug or baicalein. (D) siKEAP1 groups with drug and untreated drug. (E) siNRF2 groups with drug and untreated drug. * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001. (F) ROS production. Control group (red), baicalein group (blue), NCR group (dark green), positive control (light green), siKEAP1 with no drug (purple), siKEAP1 with baicalein (dark blue), sNRF2 with no drug (yellow), siNRF2 with baicalein (gray).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Antioxidants (Basel)