FIGURE

Fig. 3

ID
ZDB-FIG-250410-23
Publication
Rajeswari et al., 2025 - Brain monoamine changes modulate the corticotropin-releasing hormone receptor 1-mediated behavioural response to acute thermal stress in zebrafish larvae
Other Figures
All Figure Page
Back to All Figure Page
Fig. 3

Loss of Crhr1 reduces thigmotaxis in zebrafish larvae: The top panel shows the percent thigmotaxis in the wildtype (WT) and crhr1−/− larvae (KO) in response to 28 °C (28) or 33 °C (33) at 15 (A, significant interaction but no main effect, P = 0.0002) or 60 min (B, only significant interaction, P = 0.00002). Boxes represent 1 SD above and below the mean of the data (n = 92–188, 4–8 trials with 24 larvae each), the line inside the box shows the median of the data, and the whiskers indicate the minimum and maximum of all the data; boxes with different letters are significantly different (nonparametric Two-way ANOVA). The bottom panel shows the percent thigmotaxis in the wildtype without (WT) and with antalarmin (WT + An) in response to 28 °C (28) or 33 °C (33) at 15 (C, only significant interaction, P = 0.0004) or 60 min (D, no main effect but significant interaction, P = 0.0003). Boxes represent 1 SD above and below the mean of the data (n = 24–72, 1–3 trials with 24 larvae each), the line inside the box shows the median of the data, and the whiskers indicate the minimum and maximum of all the data; boxes with different letters are significantly different (nonparametric Two-way ANOVA).

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Conditions:
Observed In:
Stage: Day 6

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Molecular and Cellular Endocrinology, , Rajeswari, J.J., Gilbert, G.N.Y., Khalid, E., Vijayan, M.M., Brain monoamine changes modulate the corticotropin-releasing hormone receptor 1-mediated behavioural response to acute thermal stress in zebrafish larvae, 112494112494, Copyright (2025) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.