FIGURE 4

Effects of XCF on body weight and lipid accumulation in mice with MAFLD. (A) Body weight; (B) End body weight; (C) Food intake; Plasma TG (D), TC (E), HDL-C (F), LDL-C (G) contents; The enzymatic activity of plasma AST/GOT (H), ALT/GPT (I); Liver TG (J), TC (K) contents; (L) Micrographs of liver H&E staining; (M) Micrographs of liver Sirius red staining (bar = 20 μm). The data are presented as the means ± SEMs (n = 8). Data with different letters are significantly different (P < 0.05). NC: normal control group; HFD: high-fat diet group; XCF: xiaoji-chenpi formula extract treatment group. MAFLD, metabolic-associated fatty liver disease; TG, triglyceride; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; AST/GOT, aspartate aminotransferase/glutamic-oxal(o)acetic transaminase; ALT/GPT, alanine aminotransferase/glutamic-pyruvic transaminase; H&E, hematoxylin and eosin.