Lactobacillus fermentum E15 can improve lipid accumulation induced by a HCD in the liver and blood vessels of zebrafish. (A) Representative images of lipid accumulation in zebrafish using Oil Red O staining. (B) Zebrafish IOD values. The data are presented as mean values ± SD (n = 20). (C) Zebrafish BMI index. The data are presented as mean values ± SD (n = 20). (D) H&E staining of zebrafish liver paraffin sections (lipid droplets indicated by blue arrows). *p < 0.05, ***p < 0.001, and ns indicates that it is not statistically significant. p < 0.05 was considered as statistically significant calculated by One-way ANOVA followed by Tukey’s test.
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