Fig. 5
|
Motion indices (MI) of zebrafish phenotypic response. (a) Behavioral trace of an 11 min assay with vehicle treated animals in red, and lethal control in gray. (b–d) Increasing concentrations of endosulfan in red (195 nM in b, 390 nM in c, and 6,25 μM in d) with vehicle control plotted in gray. (e, f) Behavioral traces focusing in on the blue and green strobing assays comparing vehicle treated wells in red and lethal control in gray (e) and 195 nM endosulfan treated animals in red and vehicle in gray (f). Bottom plot is stimulus applied along the time axis. The shaded colors represent high-intensity LED light presentation, gray lines indicate solenoid tapping stimulus, and black indicates acoustic waveform application. Traces are an average motion index vector of n = 12 wells/condition. |