FIGURE

Fig. 8

ID

ZDB-FIG-250307-58

Publication

Hu et al., 2025 - Srebf2 mediates successful optic nerve axon regeneration via the mevalonate synthesis pathway

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Fig. 8

Axon regeneration into the optic tectum is dependent upon the mevalonate synthesis pathway. (A) Axon regeneration into the optic tectum is reduced upon hmgcra + hmgcrb knockdown (hmgcra + b-MO), rescued by daily supplementation with mevalonate (MVA), and accelerated by MVA treatment alone. (B) Quantification of axon regeneration in each treatment group. Colored boxes represent p < 0.05 in treated groups compared with the C-MO and/or Vehicle treated group in the corresponding column by two-way ANOVA with Fisher’s LSD post hoc test, n = 5–6 for each group. Scale bar = 500 μm

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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