FIGURE

Figure 8

ID

ZDB-FIG-250215-60

Publication

Xia et al., 2025 - ctdsp2 Knockout Induces Zebrafish Craniofacial Dysplasia via p53 Signaling Activation

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Figure 8

Analysis of somatic cell apoptosis in (A,E,I,M) control siblings, (B,F,J,N) ctdsp2^−/− mutants, (C,G,K,O) ctdsp2^−/− embryos injected with ctdsp2 mRNA, and (D,H,L,P) tp53-knockout ctdsp2^−/− embryos at 24 h post-fertilization (hpf). TUNEL staining signals, indicative of apoptotic cells, were observed in the head, pharyngeal arch, and trunk in ctdsp2^−/− mutants at 24 hpf. The signals were reduced after ctdsp2 mRNA injection. Control siblings and ctdsp2^−/− embryos with tp53 knockout showed no apparent apoptotic signals. The dotted boxes highlight areas of TUNEL staining, emphasizing specific areas where apoptosis was detected.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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