FIGURE

Fig. 7

ID

ZDB-FIG-250213-18

Publication

Martínez-López et al., 2024 - Characterization of a fish-specific Immunoglobulin-like domain-containing protein (Igldcp) in zebrafish (Danio rerio) induced after nodavirus infection

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Fig. 7

Heatmaps representing the expression of genes involved in different processes modulated by Igldcp in zebrafish larvae and the modulation of caspase a activity. The heatmaps were constructed with the TPM values of the DEGs A) with homology to NACHT, LRR and PYD domain-containing proteins (NLRP3/12-like), B) annotated as zinc-finger proteins, C) involved in cell‒cell adhesion and the extracellular matrix, and D) with a role in the cell cycle/chromatin/cytoskeleton. E) Measurement of caspase a activity in zebrafish larvae at 3 dpf after the injection of pcDNA3.1-igldcp or pcDNA3.1 at the one-cell embryo stage and incubated in the absence or presence of the caspase-1-specific inhibitor Ac-YVAD-CHO. The graphs represent the means ± SEMs of 5 independent biological replicates. Statistically significant differences are displayed as ∗ (0.01 < p < 0.05).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dev. Comp. Immunol.