FIGURE
Fig. 7
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- ZDB-FIG-250110-19
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- Smaili et al., 2024 - R391 human dominant mutation does not affect TubB4b localization and sensory hair cells structure in zebrafish inner ear and lateral line
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Fig. 7
transient expression of TubB4b and TubB4b(R391C) in SHC of 5 dpf larva. Tol2 transgenesis vectors Tg(tubB4b[Chr5]:TubB4b[Chr5]-P2A-EGFP) (A) and Tg(tubB4b[Chr5]:TubB4b(R391C)[Chr5]-P2A-EGFP) (B) were injected into 1-cell stage WT eggs. Resulting 5 dpf larva were fixed and labeled for actelylated tubulin and actin and imaged by spinning disk microscopy. Cells expressing the injected constructs are visible under green fluorescent light (EGFP wavelength). For each expression vector, anterior maculae, lateral cristae and one head neuromast are shown. Scale bar = 10 μm for all images. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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Reprinted from Developmental Biology, 517, Smaili, W., Pezet, C., Marlin, S., Ernest, S., R391 human dominant mutation does not affect TubB4b localization and sensory hair cells structure in zebrafish inner ear and lateral line, 301-316, Copyright (2024) with permission from Elsevier. Full text @ Dev. Biol.