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Fig. 1

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ZDB-FIG-241217-37
Publication
Long et al., 2024 - The influence of triiodothyronine on the immune response and extracellular matrix remodeling during zebrafish heart regeneration
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Fig. 1

Representative images of zebrafish heart post cryoinjury. (A) A super cooled probe was used to cause a cryoinjury to the ventricle in anesthetized zebrafish. The heart was then sampled at specific days post injury (dpi), sectioned along the longitudinal axis and stained with Picrosirius Red to identify the injury site. (B) Brightfield images of ventricular sections at 1-, 7-, and 10-dpi showing the injury site (is) near the apex of the ventricle (v). (C) The brightfield image at 7-dpi shows the yellow fibrin clot (fc) surrounded by brightly stained red collagen (co). (D) The polarized image highlights the densely packed (orange) collagen in the regions surrounding the faint green fibrin in the 7-dpi section. Healthy tissue of the spongy myocardium (sm) and the compact myocardium (cm) can be seen to the left of the injury site. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

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Reprinted from Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 299, Long, R.R.B., Bullingham, O.M.N., Baylis, B., Shaftoe, J.B., Dutcher, J.R., Gillis, T.E., The influence of triiodothyronine on the immune response and extracellular matrix remodeling during zebrafish heart regeneration, 111769, Copyright (2024) with permission from Elsevier. Full text @ Comp. Biochem. Physiol. A Mol. Integr. Physiol.