FIGURE

Fig. 4

ID

ZDB-FIG-241111-42

Publication

Zhu et al., 2024 - Sex disparity in zebrafish liver cell proliferation after partial hepatectomy is regulated by sex hormone receptors and the S100A1-YAP signaling cascade

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Effects of Yap1 inhibition on male zebrafish liver regeneration following PH. (A) Expression of ctgfa and cyr61 in dimethyl sulfoxide (DMSO)/verteporfin (VP)-pretreated male zebrafish livers at 6 h post-PH/sham surgery as determined by RT-qPCR. Each symbol represents one zebrafish. (B) IF staining of Pcna and Hnf4? in DMSO/VP-pretreated male zebrafish liver following PH or sham surgery. (C) Quantification of Pcna and Hnf4? double-positive proliferating hepatocytes based on B. Each symbol represents one zebrafish. (D) Changes in LBR of DMSO/VP-pretreated male LiPan zebrafish during PH-induced liver regeneration (n=3). Scale bar: 20 ?m. ns, not significant (P>0.05); *P?0.05, **P?0.01, ****P?0.0001 (two-tailed unpaired Student's t-test).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.