FIGURE

Fig. 3

ID

ZDB-FIG-240715-77

Publication

Miltenburg et al., 2024 - Characterisation of an Adult Zebrafish Model for SDHB-Associated Phaeochromocytomas and Paragangliomas

Other Figures

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Fig. 3

General histology, kidney morphology, and chromaffin cell morphology of adult heterozygous sdhb mutant and WT zebrafish. (A,D) General histology of adult heterozygous sdhb mutant (n = 34) and WT (n = 35) zebrafish (Representative images; H&E staining, 0.8× magnification). (B,E) Head kidney morphology (H&E staining, 10× magnification). (C,F) Immunohistochemical staining of tyrosine hydroxylase in the head kidney of heterozygous sdhb mutant (n = 10) and WT (n = 9) zebrafish (10× magnification). (G–J) Quantification of tyrosine hydroxylase staining (ImageJ2). Student’s t test was used to evaluate statistical significance. No significant differences were found in any of the analyses.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sdhb^rmc200/+ (AB)
Observed In:	chromaffin cell kidney
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.