FIGURE

Fig. 5

ID

ZDB-FIG-240624-73

Publication

Fagundes et al., 2024 - The generation gap in endocrine disruption: Can the integrated fish endocrine disruptor test (iFEDT) bridge the gap by assessing intergenerational effects of thyroid hormone system disruption?

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Fig. 5

Expression ( ) of A) thyroid peroxidase (tpo) and B) phosphodiesterase (pde6h) genes (mean ± 95 % confidence interval) by 4.5 d old zebrafish (Danio rerio) embryos in response to exposure of parents and/or embryos to propylthiouracil PTU. Gene expression normalised to the reference gene 18S rRNA. Control: 6 replicates; embryonic exposure: 5 replicates; parental exposure: 5 replicates; combined parental and embryonic exposure: 5 replicates. Each replicate is a sample from ca 30 pooled embryos. Different letters: significant differences between groups by Post-hoc Tukey test; capital and lowercase letters: differences in the main effect of parental exposure. Statistically significant effects of embryonic exposure: ** p < 0.01; *** p < 0.001 (ANCOVA; see Table 3).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Aquat. Toxicol.