FIGURE

Fig. 11

ID
ZDB-FIG-240509-44
Publication
Tucker et al., 2024 - Zebrafish raptor mutation inhibits the activity of mTORC1, inducing craniofacial defects due to autophagy-induced neural crest cell death
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Fig. 11

Craniofacial and body phenotypes in raptor mutants are partially rescued by genetic inhibition of autophagy. (A-D′) Dorsal and ventral view of 4 dpf fish, anterior is towards the left. (E-L) Measurements of (E-J) craniofacial elements, (K) eye width and (L) body length. From left to right, the genotypes are: raptor+/+; atg7+/+, raptor+/+; atg7−/−, raptor−/−; atg7+/+and raptor−/−; atg7−/−. The statistical analyses were conducted using one-way ANOVA followed by Tukey's honest significant difference (HSD) post-hoc test for multiple comparisons, *P<0.05, **P<0.01, ***P<0.001. The top and bottom of each box correspond to the third quartile (Q3) and first quartile (Q1), respectively. Each box covers the interquartile range (IQR), where 50% of the data lies. The median is depicted by the horizontal line within each box. The upper whisker extends to the largest value within Q3 + 1.5 * IQR. The lower whisker extends to the smallest value within Q1 - 1.5 * IQR. Any data point outside these whiskers is classified as an outlier. See Mcgill et al. (1978).

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: Day 4

Phenotype Detail
Acknowledgments
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