Fig. 5
- ID
- ZDB-FIG-240208-66
- Publication
- Zaragoza-Huesca et al., 2023 - Suramin, a drug for the treatment of trypanosomiasis, reduces the prothrombotic and metastatic phenotypes of colorectal cancer cells by inhibiting hepsin
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Suramin suppresses HPN?s effect on Caco-2 invasion in vivo. A) Fluorescence microscopy image showing invasion of Caco-2 cells in zebrafish larvae. B) Percentage of invaded larvae; comparison between larvae injected with Caco-2-EV, Caco-2-HPN, and Caco-2-HPN cells preincubated with 0.66 µM suramin. Statistical differences were calculated using the chi-square test in contingency tables. Invaded: larvae with cell invasion; No-Invaded: larvae without cell invasion; N: total number of larvae per group; * *: p-value < 0.01. |