FIGURE

Fig. 6

ID

ZDB-FIG-240201-24

Publication

Idoux et al., 2023 - A mechano- and heat-gated two-pore domain K⁺ channel controls excitability in adult zebrafish skeletal muscle

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Fig. 6

Effects of cell compression on whole-cell K+ currents in voltage-clamped adult zebrafish skeletal muscle fibers. (A) Increase in outward K+ currents (Upper traces) elicited by successive depolarizing ramps (Lower traces) bringing the membrane potential from −80 mV to +40 mV in 0.5 s every 2 s, preceded by a 50-ms pulse to −90 mV. The horizontal bar indicates the period during which cell was compressed. (B) Currents (Upper traces) before and during cell compression evoked by voltage ramps (Lower trace). Currents correspond to currents recorded at the level of * and ** in A on an expanded scale. (C) Relationship between the mean current difference (current during minus current before cell compression) and voltage (n = 6).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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