FIGURE

Fig. 3

ID

ZDB-FIG-231215-34

Publication

Nair et al., 2023 - The midbody component Prc1-like is required for microtubule reorganization during cytokinesis and dorsal determinant segregation in the early zebrafish embryo

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Spindle formation defects in the early mitotic divisions in tmi mutants. (A-C) At metaphase, wild-type asters are highly symmetric (A). In tmi mutants, spindles are often asymmetric (B) or unipolar with chromosomes clustering at one end of the structure (C). Brackets and arrowheads highlight kinetochore microtubule and centrosomes, respectively. (D,E) During anaphase, tmi mutants exhibit chromosomes that fail to segregate (E, arrowhead), which was not observed in wild type (D). Analysis is from embryos at the two- to eight-cell stages (0.751-0.25 hpf), with the specific cell cycle stage assigned by chromosome and spindle morphology.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development