FIGURE

FIGURE 2

ID

ZDB-FIG-231002-196

Publication

Meier et al., 2023 - Zebrafish as model system for the biological characterization of CK1 inhibitors

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FIGURE 2

Conditions for the synthesis of compounds G2-4 – G2-6. (a) Pyridine, CuBr, mol sieve (4 Å), DMSO, 90°C, compressed air (b) 1. NaHCO₃, Et₂O/H₂O, rt, 16 h and 2. MeOH, TEA, rt, 16 h (c) inert atm., DMF, TEA, 80°C, 2 h, EA, H₂O (d) TEA, DMF, 80°C, 2 h: 7, 10, G2-4: R1 = OCH₃, R2-R4 = H. 8, 11, G2-5: R3 = OCH₃, R1-R2-R4 = H). 9, 12, G2-6 (R2 = OCH₃, R1-R3-R4 = H).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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