FIGURE

FIGURE 5

ID

ZDB-FIG-230916-13

Publication

DeMoya et al., 2023 - Sin3a associated protein 130 kDa, sap130, plays an evolutionary conserved role in zebrafish heart development

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FIGURE 5

MZsap130a show cardiac functional deficits (A–C) Shows systole and diastole frames from recordings of live ventricular contractions in Tg(myl7:EGFP), MZsap130a;Tg(myl7:EGFP) and MZsap130b;Tg(myl7:EGFP) at 48hpf. (D, E) Quantified cardiac parameters total stroke volume (TSV) and cardiac output (CO), pvals from one-way ANOVA, error bars are SEM. Each point represents individual ventricle and color coded for 3+ experiments. For Tg(myl7:EGFP), n = 115; MZsap130a NV, n = 36; MZsap130a SV, n = 30; MZsap130b NV, n = 57; MZsap130b SV, n = 13. Scale bar 20 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sap130a^pt32a/pt32a; twu34Tg
Observed In:	heart heart contraction
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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