FIGURE

Figure 7

ID

ZDB-FIG-230828-88

Publication

Dalla Barba et al., 2023 - Modeling Sarcoglycanopathy in Danio rerio

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Figure 7

Muscle fiber integrity in the representative wild type and sgcd^−/− larvae growing in fish water with 1% methylcellulose added. (A) Representative birefringence images as obtained by viewing zebrafish with a plane polarizing filter. Microscope’s magnification 2.5X. (B) Birefringence quantification of zebrafish larvae as in (A) (wild type N = 39; sgcd^−/− N = 45). (C) Representative pictures of the phalloidin staining of whole zebrafish larvae at 5 dpf. Microscope’s magnification 20X. (D) Quantification of the fluorescence intensity of zebrafish larvae stained with phalloidin as in (B) (wild type N = 7; sgcd^−/− N = 11). Statistical analysis was performed by the Mann–Whitney test; ****, p ≤ 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sgcd^ia401/ia401
Condition:	chemical treatment by environment: methyl cellulose
Observed In:	myotome skeletal muscle cell skeletal muscle cell myoseptum skeletal muscle cell sarcomere
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.