FIGURE

Figure 9

ID

ZDB-FIG-230609-9

Publication

Perdikaris et al., 2023 - Altered GABAergic, glutamatergic and endocannabinoid signaling is accompanied by neuroinflammatory response in a zebrafish model of social withdrawal behavior

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Figure 9

Chord diagram obtained from Spearman’s correlation analysis showing the relationship between social withdrawal and anxiety-like behavior, excitation/inhibition imbalance and excessive IL-1β expression. Links indicate strong positive (+) and negative (−) significant correlations, with “r” values above 0.6 or below −0.6, respectively. Notice that glutamatergic dysfunction was associated with social withdrawal behavior whereas GABAergic and endocannabinoid system dysfunction was associated with increased anxiety. Excessive IL-1β expression in Dm was associated with anxiety-like behavior while in PM and SRF was linked both to social withdrawal and increased anxiety. p ≤ 0.05.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.