FIGURE

Fig. 3

ID

ZDB-FIG-230518-82

Publication

Doboszewska et al., 2023 - TC-G 1008 facilitates epileptogenesis by acting selectively at the GPR39 receptor but non-selectively activates CREB in the hippocampus of pentylenetetrazole-kindled mice

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

The effects of single doses of VPA (b, c), TC-G 1008 (d, e), or ZnCl₂ (f, g) on the seizure threshold in the maximal electroshock seizure threshold (MEST) test and the seizure threshold in the 6-Hz seizure threshold test. a Drugs or VEH were administered i.p. in Swiss Albino mice. 30 min later, the MEST or 6-Hz seizure threshold test was performed. b–g The doses of drugs are shown on the x-axes in mg/kg. Data are presented as CS₅₀ (in mA) values with upper 95% confidence limits. n = 20 in each group. p values were determined by the Student’s t-test or one-way ANOVA and Dunnett’s multiple comparison test. *p < 0.05, **p < 0.01, ***p < 0.001

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell. Mol. Life Sci.