FIGURE

Figure 4

ID

ZDB-FIG-230518-54

Publication

Martin et al., 2023 - Nr2f1a maintains atrial nkx2.5 expression to repress pacemaker identity within venous atrial cardiomyocytes of zebrafish

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Figure 4

Nkx2.5 expression recedes from venous pole in nr2f1a mutant atria.

(A–F’’’) IHC for Nkx2.5 (purple), Amhc (blue), and fgf13a:EGFP (SAN - green) in wild-type (WT) and nr2f1a mutant embryos from 48 to 96 hr post-fertilization (hpf). White arrows indicate border of Nkx2.5⁺ and fgf13a:EGFP⁺ cardiomyocytes. Number of embryos examined - 48 hpf: WT (n=7), nr2f1a^-/- (n=6); 72 hpf: WT (n=7), nr2f1a^-/- (n=10); 96 hpf: WT (n=14), nr2f1a^-/- (n=23). Scale bar indicates 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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