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Fig. 1

ID

ZDB-FIG-230505-12

Publication

Narumi et al., 2022 - GWAS of thyroid dysgenesis identifies a risk locus at 2q33.3 linked to regulation of Wnt signaling

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Fig. 1

Identification of the TD-associated risk locus at 2q33.3. (A) Manhattan plot of the χ² test P values of GWAS. A broken line indicates the genome-wide threshold for significance (5 × 10⁻⁸). Genotyped SNPs and imputed SNPs are plotted according to the chromosomal locations with the –log₁₀(P values) from the GWAS. (B) The upper panel shows a zoomed image of the region in chromosome 2 (hg19; chr2:208600001-209200000), showing a significant association in GWAS. Genotyped SNPs (circles) along with imputed SNPs (boxes) are shown. The lower panels display the linkage disequilibrium blocks in the 1000 Genomes project data (East Asian and European).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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