FIGURE

Figure 5

ID

ZDB-FIG-230430-31

Publication

Niu et al., 2023 - vwa1 Knockout in Zebrafish Causes Abnormal Craniofacial Chondrogenesis by Regulating FGF Pathway

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Figure 5

Increased apoptosis and decreased proliferation of cranial neural crest cell in vwa1 mutant embryos. (A,B) TUNEL staining (red fluorescence) revealed increased cell apoptosis in the cranial region and dorsal tissues of vwa1 mutant embryos at 24 hpf. SOX10 marked CNCCs. (C,D) PHH3 staining (red fluorescence) showed decreased cell proliferation in the cranial region of vwa1 mutant embryos at 30 hpf. SOX10 marked CNCCs. The pharyngeal arches are marked with dotted white circles. * p < 0.05; *** p < 0.001.

Expression Data

Gene:	EGFP
Antibody:	Ab47-h3
Fish:	ba2Tg (TU) vwa1^{pkm101/pkm101}; ba2Tg (TU)
Anatomical Terms:	cranial cartilage chondrocyte pharyngeal arch
Stage Range:	Prim-5 to Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	vwa1^{pkm101/pkm101}; ba2Tg (TU)
Observed In:	cranial neural crest cell apoptotic process pharyngeal arch pharyngeal arch cell population proliferation
Stage Range:	Prim-5 to Prim-15

Phenotype Detail

Acknowledgments

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