FIGURE
            Figure 6
- ID
- ZDB-FIG-230406-6
- Publication
- Quelle-Regaldie et al., 2023 - Severe neurometabolic phenotype in npc1-/- zebrafish with a C-terminal mutation
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                        Figure 6
                    
                    
                
                
            
        
        
    
        
            
            
| 
 Immunohistochemical study at 3 wpf with anti-NPC1 antibody in wt (A–D) and npc1−/− individuals (E–H). The square in the top picture indicates the part of the body shown in (A,E). Wt fish (A) were anti-NPC1 positive (indicated by purple staining) in the central nervous system (A) (arrow) and (B), liver (C), intestine (C) and renal tubules (D) whereas npc1−/−larvae (E) showed no staining in central nervous system (F), liver (G), intestine (G) or renal tubules (H). Scale bars in (A,E) 200 μm. Scale bars in (B–D,F–H) 50 μm. | 
                
                    
                        Expression Data
                    
                    
                
                
            
        
        
    
        
            
            
    | Antibody: | |
|---|---|
| Fish: | |
| Anatomical Terms: | |
| Stage: | Days 21-29 | 
                
                    
                        Expression Detail
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Antibody Labeling
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Phenotype Data
                    
                    
                
                
            
        
        
    
        
            
            
  
    | Fish: | |
|---|---|
| Observed In: | |
| Stage: | Days 21-29 | 
                
                    
                        Phenotype Detail
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Acknowledgments
                    
                    
                
                
            
        
        
    
        
            
            
                
                    
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      Full text @ Front. Mol. Neurosci.
                
                
            
        
        
    
    
     
        