Fig. 2
- ID
- ZDB-FIG-230112-2
- Publication
- Anderson et al., 2021 - Tbx5a and Tbx5b paralogues act in combination to control separate vectors of migration in the fin field of zebrafish
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Tbx5b mutants and knock-downs express early fin bud signaling molecules.
(a-c??) Lateral views with anterior to the left. Scale bars=10 ?m. (a-a??) shha (arrows) is expressed in the posterior mesenchyme of the fin bud at 32 hours post fertilization (hpf) in wt embryos (a), tbx5b mutant (a?), and Tbx5b knock-down (a??) embryos. (b-b??) dlx2a (arrows) is expressed in the AER of the fin bud at 32 hpf in the wt (b), tbx5b mutant (b?) and Tbx5b knock-down (b??) embryos, (c-c??) bmp4 (arrows) is expressed in the wt fin at 48 hpf (c). tbx5b mutant (c?) and Tbx5b knock-down (c??) embryos, (d-d???) Arrows indicate the normal location of fgf24 expression in the fin field at 21 hpf. Embryos are shown in a dorsal view with anterior to the top. Scale bar =100?m. (d) fgf24 is expressed in the fin field of wildtype embryos. (d?) fgf24 is absent from the fin field of Tbx5a knock-down embryos. (d??) fgf24 expression is decreased in the fin field of Tbx5b knock-down embryos. (d???) fgf24 expression is absent in double knock-down embryos. |
Reprinted from Developmental Biology, 481, Boyle-Anderson, E.A.T, Mao, Q., Ho, R.K., Tbx5a and Tbx5b paralogues act in combination to control separate vectors of migration in the fin field of zebrafish, 201-214, Copyright (2021) with permission from Elsevier. Full text @ Dev. Biol.