FIGURE
Fig. 1
- ID
- ZDB-FIG-221229-13
- Publication
- Foo et al., 2021 - Effects of Extended Pharmacological Disruption of Zebrafish Embryonic Heart Biomechanical Environment on Cardiac Function, Morphology and Gene Expression
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Fig. 1
(A) All BDM-treated embryos featured pericardial effusion (red arrowheads) and some manifested an upward-curved tail (yellow arrowhead). (B) A 5 dpf treated embryo was positioned below a wild-type (control), showing an array of phenotypic distinctions, including a shorter body length, yolk retention, and pericardial effusion. (C–C′) The cross-sectional area (red dashed line) of the control and BDM-treated ventricles was estimated. (D–D′) The measurement of cardiac looping angle from a control and a BDM-treated heart. A, atrium; V, ventricle. (E) The number of treated embryos which died or survived from 2 to 5 pdf, evaluated for control and for treated embryos at pre- and post-washout. (F) Growth retardation was observed in treated embryos at 5 dpf. (G) The size of the yolk sac among treated embryos was about 40% larger than that of control. (H) Comparison of cardiac looping angle between control and treated group. (I) Relative end-diastolic ventricular size was obtained by normalizing the cross-sectional area to that of control. For -F-I, mean and SDs were presented and two-sample t-test was used, where *P < 0.05
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Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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