FIGURE

Figure 7

ID

ZDB-FIG-221214-134

Publication

Poudel et al., 2022 - Resveratrol-Mediated Reversal of Doxorubicin-Induced Osteoclast Differentiation

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Figure 7

Inhibitory effect of resveratrol on doxorubicin-induced stimulation of osteoclasts. The ctsk reporter zebrafish transgenic line (Tg[ctsk:DsRed]) at 25 dpf was exposed to different concentrations of resveratrol (RES, 75 µM and 100 µM) alone or together with Doxorubicin (DOX, 17.2 µM) for 96 h and ctsk signal was measured in the head area. Quantification of fluorescence intensity between the treatment groups performed using fluorescent images acquired with the same parameters and analyzed with ImageJ (A), and ctsk-positive cells in the head of fish from the different treatment groups (B). One-way ANOVA, Tukey’s multiple comparisons test, *— p ≤ 0.05, **—p ≤ 0.01, ****—p ≤ 0.0001.

Expression Data

Gene:	DsRed
Fish:	mh201Tg
Conditions:	chemical treatment by environment: doxorubicin chemical treatment by environment: doxorubicin chemical treatment by environment: resveratrol
Anatomical Term:	head osteoclast
Stage:	Days 21-29

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mh201Tg
Conditions:	chemical treatment by environment: doxorubicin chemical treatment by environment: doxorubicin
Observed In:	head osteoclast osteoclast differentiation
Stage:	Days 21-29

Phenotype Detail

Acknowledgments

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