FIGURE

FIGURE 5

ID
ZDB-FIG-220924-5
Publication
Wareham et al., 2022 - Adamts10 controls transforming growth factor β family signaling that contributes to retinal ganglion cell development
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FIGURE 5

Adamts10 MO reduces pSmad3-Mediated TGFβ family signaling in zebrafish retinae. Representative fluorescent images of an uninjected (A) and adamts10 MO-injected (B)Tg(12xSBE:EGFP) embryo at 48 hpf showing fluorescence reporting of active pSmad3-mediated signaling in the retina (white arrows), brain (magenta arrows) and lens (cyan arrows, scale = 250 µm). Normalized integrated fluorescence density of uninjected, and adamts10 MO-injected Tg(12xSBE:EGFP) embryos at 48 hpf [(C), n = 21 and n = 11, respectively, ****p < 0.0001; Welch’s t-test].
Expression Data
Gene:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage: Long-pec

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage: Long-pec

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Mol Biosci
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