FIGURE
Fig. 11
- ID
- ZDB-FIG-220818-24
- Publication
- Arena et al., 2022 - Transforming growth factor-beta signaling modulates perineurial glial bridging following peripheral spinal motor nerve injury in zebrafish
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Fig. 11
Perineurial glial bridging is modulated by a positive feedback loop between TGFβ signaling and ctgfa. Summary diagram of our proposed signaling model that drives perineurial glial bridging after injury in control, 10 μM SB431542, and ctgfa−/− conditions at 0 (top panels) and 8 hpi (bottom panels). Motor axons (magenta), Schwann cells (orange), perineurial glia (light green), ctgfa expressing cells (dark green). The magnified region designates perineurial glial-specific TGFβ signaling. Dotted-lines indicate TGFβ signaling whereas solid lines indicate ctgfa signaling. Red “X”s demonstrate pathways that are inhibited or turned off in either 10 μM SB431542 treatment or ctgfa−/− larvae.
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Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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