FIGURE

Fig. 5

ID
ZDB-FIG-220706-106
Publication
Lozano-Gil et al., 2022 - Gasdermin E mediates pyroptotic cell death of neutrophils and macrophages in a zebrafish model of chronic skin inflammation
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Fig. 5

Fig. 5. Gsdme mediates pyroptotic cell death in neutrophil in zebrafish with skin inflammation. One-cell stage zebrafish eggs from Tg(mpx:gal4.vp16)/Tg(uas:gbp4) (see Fig. 4A) were microinjected with control or spint1a crRNA/Cas9 complexes. At 1 dpf, embryos were treated with the specific inhibitors of Gsdmea and Gsdmeb, Ac-SEVD-CMK (A) and Ac-FEID-CMK (B), respectively, and neutrophils were stained at 3 dpf with Sudan black. *p < 0.05; ***p < 0.001; n.s., non-significant.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
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