FIGURE

Fig. 5

ID

ZDB-FIG-220617-42

Publication

Rosello et al., 2022 - Disease modeling by efficient genome editing using a near PAM-less base editor in vivo

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Fig. 5

On-target and potential off-target analyses by NGS sequencing.

a–c Potential off-target sequences with mismatches in red of the nras NAN sgRNA (a), tp53 sgRNA (b), and tyr(W273*) NAN sgRNA (c). d–g NGS sequencing was made on pools of embryos with at least 6800 analyzed reads for each condition. NGS analyses of on-targets are also shown in Supplementary Fig.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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