FIGURE

Figure 4—figure supplement 1.

ID

ZDB-FIG-220522-18

Publication

Solman et al., 2022 - Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects

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Figure 4—figure supplement 1.

Distinct expression profiles of mutant zebrafish embryos in pseudotime.

(A) Identities of the four clusters of HSPCs of Shp2^wt, Shp2^D61G/wt and Shp2^D61G/D61G genotypes from the trajectory in Figure 4, ordered in pseudotime. (B) Heat map showing scaled expression (log TPM [transcripts per million] values) of representative genes (y-axis) in cells of Shp2^wt, Shp2^D61G/wt, and Shp2^D61G/D61G genotypes from the selected trajectory route, ordered along the pseudotime (x-axis). The cell type and pseudotime are annotated above the heat map.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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