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ZDB-FIG-220520-23

Publication

Pan et al., 2022 - Gnetum montanum extract induces apoptosis by inhibiting the activation of AKT in SW480 human colon cancer cells

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Fig. 2

Figure 2. Effect of GME on the viability of colon cancer cells SW480. (A) Colon cancer cells SW480 were treated with GME at concentrations of 0?120??g/mL in triplicates for 24, 48, and 72?h. (B) The human normal colonic epithelial cells NCM460 were treated with GME at concentrations of 0?120??g/mL in triplicates for 24, 48, and 72?h. Cell viability was measured by MTS assay. (C) The SW480 cells were treated with GME for 48?h. Apoptotic bodies were stained with DAPI (4?,6-diamidino-2-phenylindole). The cell morphology changed significantly, and the nucleus contracted and rounded. The cells were observed under the Operetta CLS high-content analysis system at DAPI pathway.

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