FIGURE

Fig. 2

ID

ZDB-FIG-220203-69

Publication

Barthelson et al., 2021 - In-Frame and Frameshift Mutations in Zebrafish Presenilin 2 Affect Different Cellular Functions in Young Adult Brains

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

A) Heatmap showing the significant KEGG [29] gene sets in psen2 heterozygous mutant brains, clustered based on their Euclidean distance. The columns represent the gene sets which are significant in at least one comparison, and the rows are the two comparisons. The color of each cell represents the significance value with more significant gene sets appearing lighter. The numbers within each cell are the FDR-adjusted harmonic mean p-values (HMP). ns, not significant. B) Heatmap indicating the logFC of genes in the KEGG_RIBOSOME gene set in EOfAD/+ and FS/+ brains. C) Upset plot showing the overlap of leading edge genes from the fgsea algorithm in gene sets found to be altered in EOfAD-like/+ brains, and D) FS/+ brains. See the online version for color.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J Alzheimers Dis Rep