FIGURE

Fig 8

ID

ZDB-FIG-220131-494

Publication

Chow et al., 2022 - Cardiac forces regulate zebrafish heart valve delamination by modulating Nfat signaling

Other Figures

All Figure Page

Back to All Figure Page

Fig 8

Delamination defects in gata1 mutants leads to increased cell proliferation.

(A) Number of cells in different valve regions at 98 hpf. p-Values based on unpaired t test. (B) Representative images of 98 hpf gata1 control and mutant valves incubated with EdU from 74 to 98 hpf. Scale bars: 20 μm. (C) Graph showing number of EdU positive cells in 98 hpf gata1 controls and mutant valves. p-Values are based on unpaired t tests. (D) Graph showing fraction valve cells that stained positive for EdU in 98 hpf gata1 controls and mutant valves. p-Values are based on Welch t test. (E) Graph showing fraction of abluminal and luminal cells in 98 hpf gata1 controls and mutant valves that stained positive for EdU. p-Values are based on 2-way ANOVA. AVC, atrioventricular canal; hpf, hours postfertilization; VIC, valve interstitial cell.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Biol.