FIGURE

FIGURE 4

ID
ZDB-FIG-211025-64
Publication
Gong et al., 2021 - Nitazoxanide induced myocardial injury in zebrafish embryos by activating oxidative stress response
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FIGURE 4

NTZ affected the proliferation of cardiomyocytes and induced apoptosis. Live Tg (myl7: GFP) zebrafish embryos were exposed to vehicle control (0.1% DMSO) or 2.0 mg/L NTZ at 6 hpf. The samples were taken at 72 hpf. (A) Representative images of fluorescence staining of PCNA showed proliferating cells. The white arrows indicate positive signals of proliferating cardiomyocytes. (B) Representative images of TUNEL staining showing apoptotic cells. The white arrow indicates a positive signal of apoptotic cardiomyocytes. Scale bar: 50 μm in panels a and b

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