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Fig. 2

ID

ZDB-FIG-211025-43

Publication

Brun et al., 2021 - Developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish

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Fig. 2

Effect of PCBs on startle response in 6 dpf zebrafish.

a Representative short-latency C-bend (SLC) and long-latency C-bend (LLC) startle response of a control zebrafish larva at 6 dpf in comparison to a typical response of a PCB153 treated larva. b Vibro-acoustic startle latency at highest stimulus intensity (43 dB) in vehicle control (n = 448), NDL PCB153 1000 nM (n = 115), NDL PCB153 100 nM (n = 226), NDL PCB153 30 nM (n = 117), NDL PCB153 10 nM (n = 112), NDL PCB138 (n = 68), NDL PCB118 (n = 99), NDL PCB52 (n = 97), and DL PCB126 (n = 86) exposed larvae. c Bias of SLC and LLC and d response rate of different exposure groups at different vibro-acoustic intensities. All data points are biologically independent samples from at least three independent experiments and mean ± SEM shown in the plots of (c, d). Binomial GLM was used for statistical analysis in (c, d). Significant differences to DMSO controls (p < 0.01) are indicated by open symbols.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

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