ZFIN ID: ZDB-FIG-211007-79
Ansar et al., 2020 - Biallelic variants in PSMB1 encoding the proteasome subunit β6 cause impairment of proteasome function, microcephaly, intellectual disability, developmental delay and short stature. Human molecular genetics   29(7):1132-1143 Full text @ Hum. Mol. Genet.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Day 4 to Day 5

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
zf498Tg + CRISPR1-psmb1 + CRISPR2-psmb1 standard conditions Day 5 brain decreased size, abnormal
Day 5 brain morphology, abnormal
zf498Tg + CRISPR3-psmb1 standard conditions Day 5 brain decreased size, abnormal
Day 5 brain morphology, abnormal
zf498Tg + MO1-psmb1 standard conditions Day 4 brain decreased size, abnormal
Day 4 brain decreased width, abnormal
Day 4 brain morphology, abnormal
zf498Tg + MO2-psmb1 standard conditions Day 4 brain decreased size, abnormal
Day 4 brain decreased width, abnormal
Day 4 brain morphology, abnormal
Full text @ Hum. Mol. Genet.