FIGURE

Figure 2

ID

ZDB-FIG-210902-324

Publication

Noschka et al., 2021 - Gran1: A Granulysin-Derived Peptide with Potent Activity against Intracellular Mycobacterium tuberculosis

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Figure 2

Activity of Gran1 against extracellular mycobacteria: Extracellular mycobacteria (2 × 10⁶) were incubated with increasing concentrations of Gran1 followed by incubation with ³H-Uracil for 18 h. The ³H-Uracil uptake was measured by scintillation counting. Antibacterial activity was determined for (A) slow-growing strains M. kansasii (n = 4), M. avium (n = 5), M. bovis BCG (n = 5) and (B) fast-growing strains M. fortuitum (n = 4), M. vaccae (n = 5), and M. smegmatis (n = 5). Data points show the mean antibacterial activity (%) ± SEM calculated from triplicates of each independent experiment. Dotted horizontal lines indicate background activity of diluent control.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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