FIGURE

Fig. 4

ID

ZDB-FIG-210729-20

Publication

Li et al., 2021 - Efficacy of Fenfluramine and Norfenfluramine Enantiomers and Various Antiepileptic Drugs in a Zebrafish Model of Dravet Syndrome

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Fig. 4

The total uptake of (+)-FFA (A), (−)-FFA (B), (+)-norFFA (C) and (−)-norFFA (D) in the larvae head after different exposure times (30 min, 4 h and 22 h). The concentration in the head of larvae pre-exposed to (+)-FFA (A), (−)-FFA (B), (+)-norFFA (C) and (−)-norFFA (D) at their respective MTCs for 30 min, 4 h and 22 h, separately, and total uptake of compound = compound concentration/head weight. With 5 larvae heads for each sample, and 5 replicates for a total of 25 larvae heads per treatment. Statistical analysis: one-way ANOVA with Dunnett’s multiple comparison test. Significance levels: ^*p ≤ 0.05, ^**p ≤ 0.01, ^***p ≤ 0.001, ^****p ≤ 0.0001. WT wild type, VHC vehicle, FFA fenfluramine, norFFA norfenfluramine

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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