FIGURE

Figure 3

ID

ZDB-FIG-210707-48

Publication

Nishimura et al., 2021 - Toxicity of Jegosaponins A and B from Styrax japonica Siebold et al. Zuccarini in Prostate Cancer Cells and Zebrafish Embryos Resulting from Increased Membrane Permeability

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Figure 3

Jegosaponin A and B increase cell membrane permeability. (a) Haemolysis of RBCs by jegosaponin A and B. n = 3, error bars indicate SD. (b) Increase in cell membrane permeability of PC-3 cells treated with jegosaponin A and B. Purple indicates membrane impermeable DRAQ7-stained nucleus. (c) Quantitative analysis of (b). n = 3, error bars indicate SD. * p < 0.05 and ** p < 0.01 vs. control (0 μM jegosaponin A); # p < 0.05 and ## p < 0.01 vs. control (0 μM jegosaponin B). (d) Increase of cell membrane permeability of 48 hpf zebrafish by jegosaponin A and B. Purple indicates membrane impermeable DRAQ7-stained nucleus.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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