Figure 5

Anatomical distribution of putative burst neurons in the zebrafish hindbrain. Each colored ball represents an identified saccade-associated neuron. (a,b) Dorsal and sagittal cell maps for CW-LETN-RENT and CCW-LENT-RETN neurons. (c) Dorsal cell map for pooled Helmholtz-like neurons representing clockwise (RENT type and LETN type) and counter-clockwise (RETN type and LENT type) directions, as well as vergence (convergent, divergent) neurons. (d) Sagittal schematic illustrating the position of the major cluster of SA neurons (red) relative to the position of other neuron types (grey) identified in a previous study (adapted from Brysch, Leyden and Arrenberg¹⁶, licensed under CC BY 4.0 (http://creativecommons.org/licenses/by/4.0/)). In (a–c), the trapezoid box represents the abducens nucleus, and the blue cones represent the Mauthner (M) cell bodies. The medial longitudinal fasciculus is represented by the thick blue lines parallel to the larval midline. D dorsal; V ventral; A anterior; P posterior; DV dorsal–ventral; AP anterior–posterior. Data from n = 30 larvae is merged in the anatomical plots (a–c), corresponding to approximately 3.5–7 completely imaged hindbrains in the range of − 80 to 40 µm (see “Methods”).