FIGURE

Figure 4

ID

ZDB-FIG-210520-44

Publication

Dong et al., 2021 - Inhibitory Effects of Euphorbia ebracteolata Hayata Extract ECB on Melanoma-Induced Hyperplasia of Blood Vessels in Zebrafish Embryos

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Figure 4

Effect of Euphorbiaceae compound B (ECB) on metastasis of melanoma cells in zebrafish xenografts. Zebrafish embryos were injected with A2058 cells at 48 hpf and observed at 6 hpi, 24 hpi, and 48 hpi, respectively. (a) Not injected. (b?d) A2058 cells were injected into zebrafish embryos at 48 hpf and observed at 6 hpi, 24 hpi, and 48 hpi, respectively. (e) A2058 cells were injected into zebrafish embryos and treated with 20?�g/mL ECB for 24?h and observed at 48 hpi. (f) A2058 cells were injected into zebrafish embryos and treated with 1?�M PLX4720 (PLX) for 24?h and observed at 48 hpi. (g) The area of CM-DiI labeling (melanoma cell) in the zebrafish embryos. Scale bar?=?200?�m. indicates a significant difference (p<0.001).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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