FIGURE

Fig. 5

ID

ZDB-FIG-210517-20

Publication

Ping et al., 2021 - KPNA4 is involved in cataract formation via the nuclear import of p53

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Fig. 5

The expression pattern of p53 in H₂O₂-induced apoptotic cells and kpna4 knockout zebrafish. (A) HLE cells stained for KPNA4 (green) and p53 (red) in the normal control (NC) group or 200 μmol/L H₂O₂ treatment. (B-C) Western blot with KPNA4 and p53 in the NC and 200 μmol/L H₂O₂ treatment group in HLE cells or 293 T cells. (D-E) The relative intensity of KPNA4/actin and p53/actin of three independent experiments in HLE cells or 293 T cells. (F) Immunofluorescence for p53 in the lens of 72 hpf WT and kpna4 knockout zebrafish. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

Expression Data

Antibody:	Ab16-tp53
Fish:	AB kpna4^{zf3529/zf3529} (AB)
Anatomical Term:	lens
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	kpna4^{zf3529/zf3529} (AB)
Observed In:	lens
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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Reprinted from Gene, 786, Ping, X., Cheng, Y., Bao, J., Shi, K., Zou, J., Shentu, X., KPNA4 is involved in cataract formation via the nuclear import of p53, 145621, Copyright (2021) with permission from Elsevier. Full text @ Gene