FIGURE

Fig. 1

ID

ZDB-FIG-210510-17

Publication

Barker et al., 2020 - Functional, molecular and morphological heterogeneity of superficial interneurons in the larval zebrafish tectum

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

Many Gal4s1156t+ SINs are strongly tuned to changes in whole‐field luminance. (a) Example SIN from a 7dpf Gal4s1156t × UAS:GCaMP6s larva shows consistent responses (shown as ΔF/F) to whole‐field changes in luminance. (b) Responses to whole‐field luminance are highly consistent across larvae. Responses from five SINs from four Gal4s1156t × UAS:GCaMP6s larvae. (c) Gal4s1156t+ SINs are more responsive to darkening (decreasing luminance) whole‐field flashes than brightening (increasing luminance) whole‐field flashes (unpaired t‐test, p < .0001). (d, e) Electrophysiological recordings show increased excitatory synaptic input in response to transitions between light ON and light OFF conditions. (d) Four example traces from neurons targeted in Gal4s1156t × UAS:Kaede. EPSCs occur with greater frequency during low luminance (light OFF) conditions. (e) Total excitatory postsynaptic current is plotted for OFF and ON light conditions. For (c), n = 47 cells from 17 larvae. *** denotes p < .0005; Scale bar in (d), 20 pA, 200 ms. Error bars are SEM. Visual stimulus is shown above the corresponding example traces in (a), (b), and (d)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Comp. Neurol.